Alzheimer, Dr Killick, Parker discussed on This Week in Science


Disrupting the cycle of beta amyloid production that comes from the synapse loss makes perfect sense. Importantly, this is Dr Killick again. Importantly, I work has shown that we may be. We may already be in a position to block the feedback. Loop with a drug called vassal fast food Bill, something that's at drink that's being used and some countries for stroke. Currently, we have convincingly shown this drug can protect snaps, his memory in animal models with Alzheimer's, and at the same time reduces the amount of amyloid that is in the brain researchers found that in mice, engineered to develop large deposits of beta amyloid. Brains, the age just two weeks of treatment with the drug dramatically reduced the deposits researchers at king's Alexander seeking funding to run early stage on sufferers of Alzheimer's, determine if it can actually improve brain health, prevent cognitive decline, so cool. So there's that. We also had the few other stories targeting Alzheimer's, some new discoveries that have happened in in the last years. And I think this story caught my eye this week. Because we're saying goodbye to a member of my extended family this week who died after a long battle with Alzheimer's Parker, who many people may have actually seen and gotten to know little bit. 'cause he played grandpa, Shawn Brady on days of our lives, the patriarch of the family there for about twenty years. And what you saw on screen was very much who Frank was in person. He's warm, loving guy, and he liked to light up a room with the song. So this is this is so we were talking to few three weeks ago about some new discoveries about the garbage removal system being disrupted the the lymph notable system that's around the brain that was only discovered back in twenty fourteen. We live at this time when when we're so close, we're so close to to ending the suffering of so many people at the hands of these awful diseases. So I wish I'm much luck in there can in the future on this research. And even though we kind of tend to avoid talking about the potential possible may be cures of all the medical conditions because there's so much research going on that it's hard to just keep talking about the potentials. When they're getting close to getting close to trials on a drug, it's time for those who if you know somebody, you know who who suffering, look for one of these clinical trials. See if there's one in your area. See if there's somebody somewhere they can sign up and be part of that test group to see because without a whole lot of options. The next best thing is is worth trying well and Alzheimer's is something that we're still not a hundred percent. Sure how it happens or where it comes from, you know, we, I feel like we settled recently that it's it's definitely a mixture of environmental and genetic factors, but it's when it's something that it's it's becoming. It's still really difficult to predict when and where it's going to happen. And it's also really difficult to prevent the treatment. It's our the thing to look at for this problem at this point. So right yet, we, we don't know where, yeah, you're right. We don't know exactly how it gets its start where the seat, but so many of us are affected by family members and friends who are affected by this disorder. And yeah, I've had family members succumb to Alzheimer's as well, and it's not. It's it's no fun because people lose themselves. They lose. They were and they in because their their brain start shutting down and they start losing memories, or they start the ability to create new memories isn't there anymore. They live in the past more than in the present now..

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