Antarctica, Fran Arctic, Concordia Station discussed on Houston We Have a Podcast
To the immune system in several in Arctic bases in our two guys amount. And so some of the interior bases like south pole station or concordia you get this sleep. Alterations, the security and lost this twenty four hour darkness. And you also have a persistent hyperbaric poxy a- coastal an Arctic winner over you have a normal environment, but you also have that extreme environment. And so yes, in flight sleep is important. It can affect the immune system and these are the tools we would look us to look at this phenomenon on the ground and Arctic. Oh, wow, I, I mean, if I was going to go to Antarctica, I'd probably choose the twenty four hour light that would probably make me feel better. They have that during the summer. Yeah. And then you get to the winner. They get the twenty four. I don't know why you'd sign up for the NRT winter trip, but how long are they staying there to to really get enough data to to understand this circadian change crews performing a winner over in Antarctica in most of the bases. The typical mission Gration is about a year that makes it a fantastic ground-based spaceflight analog where we want a pro- prolong mission duration. So the the year is dictated by the calendar year. Generally during the summer period in art ago, you have resupply of these basis, crew swaps happen. And then the last cruise leave for the winner over period and the crews do their one year duration with the middle of the NRT winner being the three months or so of twenty four hour darkness. Do we have enough data to understand what's happening to the immune system because of these sleep studies were are? Is there still a lot that we'd still need to look into? Well, we've been if you're asking me about Antarctica, yes, we're, we're learning more. People have been looking at the reactivation of latent herpes viruses, which is a nice biomarker for immune dis- regulation in entered a winner over and during spaceflight for decades docked. Wayne Pearson, an Esa was one of the pioneers for using viral DNA in saliva as a biomarker for immune dis- regulation. But more recently studies I mentioned with with our European collaborators are helping us to really define comprehensively what happens to the immune system during Antarctic winner over. And so a lot of the same essays that we use to characterize immune changes in astronauts have non is s we simply translate those essays to Antarctica and employ them there. And it gives us a very nice flight to ground comparison right. What's interesting is the different ways you have to change things to implement studies in these two different locations. And so for spaceflight, it's very difficult to take our laboratory there or or get a lot of crew time to do a lot of processing these samples. So we'll draw blood sample. We'll bring it back to earth and we can get ambient blood sample in our hands and about thirty seven hours that was collected during spaceflight Fran Arctic winner over you don't have a rapid return for samples like this, and so you have to, but you do have the ability to deploy a little more equipment and so it concordia station in particular, we deployed flow Saitama, tres various sample processing apparatus, and we'll have the crews do a little more remote processing samples during their winter over activities. What we're chasing the same data flight to ground comparison is very important for validating ground based analog, which is a nice tool to help you understand what's happening during flight, and also a nice location then you can probably use. Test your countermeasures, right? Yeah, there's a lot of other Bill watt of other research going onto. That's you. You use the word analogue this. That's these sort of studies where you're putting them in a in an environment. That's, you know, it's not like you're taking a vacation. I wouldn't call that a vacation at all, but you're really just putting him in this environment early understand what is like in this in these hostile environments in article is one of them. There's another one called Mars, five hundred to what's happening there are we are we doing similar studies Mars. Five hundred is a very interesting spaceflight Annalong that's happening in Russia at the institute for by medical problems in Moscow..